Analysis of Aiolos (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0015-LGZ)

Introduction

The Ikaros family has a C2H2 zinc finger structure (CX2-3-C-X3-Phe-XS-L-X2-H-X3-H), which is essential for the early genesis, development and normal function of lymphocytes and other hematopoietic cells.
Aiolos belongs to the zinc finger family of Ikaros transcription factors and is expressed by various immune cells. Aiolos can form homologous or heterodimer with Ikaros, or interact with other non-Ikaros zinc finger family transcription factors and epigenetic regulators to regulate gene expression through direct binding of its zinc finger motifs to target DNA.