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Also known as: GM133; CAP350
The product of this gene is a large protein with a CAP-Gly domain, usually found in cytoskeleton-associated proteins. The encoded protein is mainly localized in the centrosome, which is the main microtubule organizing center in animal cells and is a non-membrane organelle. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also related to the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been identified, but their full-length nature has not been determined.
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