Analysis of COQ8A Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0884-LGZ)

Introduction

Official Full Name: coenzyme Q8A<br />Also known as: COQ8; ADCK3; ARCA2; CABC1; SCAR9; COQ10D4<br />This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.