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Official Full Name: ERCC excision repair 4, endonuclease catalytic subunit
Also known as: XPF; RAD1; FANCQ; XFEPS; ERCC11
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).