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Interferon gamma (IFN-γ) is a soluble dimeric cytokine, the only member of type II interferons. It is mainly secreted by natural killer cells (NK) and natural killer T cells (NKT) cells, and plays a role in innate immunity; in the process of antigen-specific immunity, it is secreted by CD4 Th1 and CD8 cytotoxic T cells.
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