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Analysis of IL-22 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0332-LGZ)

Introduction

Interleukin (IL)-22 belongs to the IL-10 family of cytokines. IL-22 exerts its biological effects through class 2 members of the cytokine receptor family. CD4+ T helper (Th) cells that mainly produce IL-22 are called Th22 cells. IL-22/Th22 cells are functionally related to IL-17/Th17 cells, but there are significant differences. Both IL-22 and IL-17 are cytokines that recruit neutrophils during microbial invasion. In chronic inflammation, IL-22 mediates protective and regenerative processes, whereas IL-17 cytokine tends to induce inflammation.




Principle

Detection Technique: MSD Hypersensitive Multi-Factor Electrochemiluminescence
Capture Antibody: Rat Monoclonal
Detection Antibody: Goat Polyclonal
Recombinant Standards: Expressed in E. coli

Applications

Cytokines & Chemokines, Immunology/Inflammation

Procedure

1. Coat the capture antibody on the well plate.
2. Add samples/calibrators.
3. Add detection antibody.
4. Read the plate and analyze the data.

Materials

• Sample Type: Serum, Plasma, Cell Culture Supernatant, Urine
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