Analysis of INS-IGF2 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2263-LGZ)

Introduction

Official Full Name: INS-IGF2 readthrough
Also known as: INSIGF
This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye.