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Official Full Name: potassium inwardly rectifying channel subfamily J member 10
Also known as: KIR1.2; KIR4.1; SESAME; BIRK-10; KCNJ13-PEN
The gene encodes a member of a family of inward rectifier-type potassium channels that are characterized by a greater preference for allowing potassium to flow in rather than out of the cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for potassium buffering in glial cells in the brain. Mutations in this gene are associated with susceptibility to seizures in a common idiopathic generalized epilepsy syndrome.