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Gene description: VISTA enhancer hs1937
Gene type: biological region
This locus represents a conserved genomic element that can function as an enhancer. It can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic branchial arch, dorsal root ganglion, ear, heart, hindbrain, limb and other tissues of transgenic mice. A subregion marked by the H3K4me1 histone modification was also shown to be an active enhancer by ChIP-STARR-seq in naive human embryonic stem cells.