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Nerve cell adhesion molecule 1(CD56) is mainly distributed in most cells, tissues and tumors of neuroectodermal origin, mainly used in retinoblastoma, medulloblastoma, astrocytoma, neuroblastoma and other tumors. The ligand is NCAM-1, and CD56 plays an important role in intercellular adhesion. The CD56 domain is homologous to the immunoglobulin domain.