Analysis of PROC Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1471-LGZ)

Introduction

Official Full Name: protein C, inactivator of coagulation factors Va and VIIIa<br />Also known as: PC; APC; PROC1; THPH3; THPH4<br />This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.