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Stem cell factor (SCF), also known as c-kit ligand, is a basic hematopoietic stem cell growth factor with anti-apoptotic function. The human SCF gene encodes a leader peptide, an extracellular portion of 189 amino acids, a hydrophobic transmembrane region and an intracellular region. Natural SCF exists in a membrane-bound form or in a soluble form. The soluble portion is 164 or 165 amino acids from the beginning of the extracellular portion.