Analysis of TFF2 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0569-LGZ)

Introduction

Trefoil factor 2 (TFF2), is a protein encoded by the TFF2 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40 amino acid domain containing three conserved disulfide bonds. They are stable secreted proteins expressed in the gastrointestinal mucosa. Their function has not been defined, but they protect the mucosa from invasion, stabilize the mucus layer and influence the healing of the epithelium. The encoded protein inhibits gastrointestinal motility and gastric acid secretion and may function as a structural component of gastric mucus.