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Official Full Name: TNF superfamily member 4
Also known as: GP34; CD252; OX4OL; TXGP1; CD134L; OX-40L; TNLG2B
This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.