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Serum albumins (SAs) are the major soluble proteins in the circulatory system that acts as a depot and also a carrier for many endogenous and exogenous compounds such as drugs. Bovine SA (BSA) is the most frequently used protein in the drug-protein interaction studies due to its structural homology with human SA (HSA), cheapness, easy availability and considerable stability. It is a large monomeric protein (66 kDa) consisting of about 583 amino acid residues as single chain.
Neomycin, an antibiotic, is used to prevent or treat skin infections caused by bacteria. Oral neomycin is used to help lessen the symptoms of hepatic coma, a complication of liver disease. In addition, it may be used with another medicine before any surgery affecting the bowels to help prevent infection during surgery.