Determination of Melting Point of Prodrugs of Sulfonamides as an Azo Derivatives of Carvacrol by Open Capillary Method (CAT#: STEM-PPA-0090-YJL)

Introduction

Prodrug is a newer category of drug, which are inactive forms of drug, but can be biotransformed into active form in vivo by means of enzymatically or chemically. A prodrug can be used to get better drug delivery action, pharmacological activity and pharmacokinetics of a parent drug molecule.
Carvacrol is a naturally occurring monoterpenoid found in essential oil of origanum Vulgare, oil of thyme. In some studies it is shown that carvacrol can make apoptosis (cell destruction) in cancer cells. Carvacrol has highest activity against E. coli because of this, carvacrol may be suggested to use routinely to promote gastrointestinal health and to avoid deadly food poisoning.
Azo compounds forms a new class in synthetic organic chemistry which possess various applications mostly as dyes and pigments. Now a day azo compounds are also used in the field of medicinal chemistry. Azo compounds exhibits various properties including antibacterial and antifungal.