Human Recombinant Apolipoprotein A-I, STEMCELL Technologies (CAT#: STEM-CT-0764-ZJF)

A member of the apolipoprotein family, Apolipoprotein A-I (apo A-I) is a major glycoprotein component of high density lipoprotein (HDL) particles (Frank & Marcel) which facilitate the reverse transport of cholesterol from peripheral tissues to the liver. Apo A-I binds to the scavenger receptor SR-A1, allowing HDL particles to interact with cells in peripheral tissues (Neyen et al.), and is involved in the esterification of cholesterol, acting as a cofactor for lecithin cholesterol acyltransferase (LCAT; Frohlich). Apo A-I has been shown to bind to the scavenger receptor SR-B1 (Williams et al.) and the beta chain of ATP synthase (Martinez et al.) on hepatocytes, highlighting its importance in HDL endocytosis. Mutations in the APOA1 encoding gene may result in dysregulated HDL levels, leading to an increased risk of amyloidosis and ischemic heart disease (Haase et al.; Obici et al.). This protein product contains a His-residue tag at the amino end of the polypeptide chain. This protein product contains a His-residue tag at the amino end of the polypeptide chain. For consistency and reproducibility across your applications, sclerostin from STEMCELL comes lyophilized with ≥ 92% purity.

Subtype: Cytokines
Alternatives Names: Apolipoprotein A1
Species: Human
Area of Interest: Metabolism
Purity: ≥ 92%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

Human Recombinant Autotaxin, STEMCELL Technologies
Human Recombinant Fetuin A, STEMCELL Technologies
Human Recombinant ANGPTL2, STEMCELL Technologies
Human Recombinant IL-37, STEMCELL Technologies