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Human Recombinant IL-22, STEMCELL Technologies (CAT#: STEM-CT-0920-ZJF)

Highlights

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

Cat Number: STEM-CT-0920-ZJF

Application: Interleukin 22, for cell activation, expansion, or differentiation

Model: 78038

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Description

Interleukin 22 (IL-22) is a class 2 α-helical cytokine that signals through the class 2 cytokine receptor and activates the JAK/STAT pathway. IL-22 is secreted by Th1, Th2, Tc22, and γδ T cells, dendritic, mast and NK cells. It stimulates expression of antimicrobial peptides from epithelial cells, thus hindering bacterial infections. Depending on the interactions with other cytokines, IL-22 can either promote inflammation or prevent tissue destruction by regulating host defense and tissue homeostasis at barrier surfaces (Sonnenberg et al.).

Specification

Subtype: Cytokines
Cell Type: Airway Cells, Hepatic Cells, Intestinal Cells, Keratinocytes, T Cells, T Cells, CD4+, T Cells, CD8+
Species: Human
Area of Interest: Epithelial Cell Biology, Immunology
Purity: > 98%

Features

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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