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Peptidomics takes endogenous peptides and low-molecular-weight proteins of the body as the research object, and studies the structure, function, change rules and related relationships of the peptide group. There is no clear boundary between polypeptides and proteins, and proteins with a molecular weight of less than 10kDa are generally considered to be polypeptides. Peptidomics and proteomics are both supplements to genomics. Peptides can reflect the synthesis, processing and degradation of proteins under different physiological and pathological conditions, and at the same time regulate gene expression and substance metabolism. Therefore, peptidomics is considered as a "bridge" between proteomics and metabolomics.