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Rheumatoid arthritis (RA) is a systemic autoimmune disease mainly characterized by joint disease. Chronic, progressive, and aggressive joint inflammation is the main manifestation. The clinical features are joint redness, swelling, pain, or even stiffness, formation of osteoclasts, and damage to joint bone. Severe cases can lead to joint deformity and even loss of function, with a high disability rate . RA mostly occurs in middle-aged and elderly women, and the overall incidence in my country is about 0.3-0.4%. The pathogenesis is not yet clear, and it may be caused by a combination of factors such as genetics, infection, and environment.