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Phospholipid vesicles, also known as liposomes, are small spherical structures made up of a lipid bilayer. Phospholipid vesicles have a bilayer structure when dispersed in aqueous medium. Fatty acid chains of phospholipids concern formation of bilayers and result in different vesicle sizes under the same preparatory conditions and energy input. The lipid bilayer is composed of phospholipids, which have a hydrophilic (water-loving) head and a hydrophobic (water-fearing) tail. This structure allows liposomes to encapsulate both hydrophilic and hydrophobic molecules within their interior or between their bilayers. Small particle sizes have a greater advantage in colloidal stability. Liposomes have a wide range of applications in drug delivery, cosmetics, and research due to their ability to protect and transport molecules.