The Determination of Raloxifene Using Gold Nanoparticle as a Probe by Resonance Rayleigh Scattering (CAT#: STEM-ST-0059-YJL)

Introduction

Gold nanoparticles are paid much attention in the field of science and technology and their applications in analytical chemistry have aroused many analysts' interest. The chemical modified gold nanoparticles used as probes or biochemical sensors have been increasingly applied to spectral analysis, immunoassay and electrochemical analysis. They can be used to the detection of DNA hybridisation, the determination of trace DNA and the immunoassay of proteins and they can be used for the determination of trace metal ions.
Raloxifene hydrochloride (Abbr. Ralo) is a 3-aroyl-2arylbenzo[b] thiophene derivative with triarylethylene nonstereoidal structure. Ralo belongs to selective estrogen receptor modulators (SERMs). At present, it has been applied to the prevention of osteoporosis, the prevention of breast cancer, the inhibition of the growth of uterine leiomyomas and the therapy of cardiovascular disease, etc.