Analysis Biomolecular Interactions of Influenza A virus (IAV)–Receptor by BLI (CAT#: STEM-MB-0089-CJ)

Introduction

Influenza A virus (IAV) causes influenza in birds and some mammals, and is the only species of the genus Alphainfluenzavirus of the virus family Orthomyxoviridae. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics. Influenza A vaccine for humans has been developed and many countries have stockpiled it to allow a quick administration to the population in the event of an avian influenza pandemic.Sialic acids (SAs) of cell surface glycoproteins and glycolipids are the receptors for the influenza virus, recognized by the viral glycoprotein hemagglutinin.