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Official Full Name: amyloid P component, serum
Also known as: SAP; PTX2; HEL-S-92n
The protein encoded by this gene is a glycoprotein belonging to the pentosidine protein family with a typical pentamer structure. These family members share considerable sequence homology, which is thought to be the result of gene duplication. Binding of the encoded protein to the pathological amyloid crossfold protein suggests a possible role as a chaperone. This protein is also thought to control the degradation of chromatin. Studies have shown that the protein binds to apoptotic cells at an early stage, raising the possibility that it is involved in the processing of apoptotic cells in vivo.