Analysis of ATG4B Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1550-LGZ)

Introduction

Official Full Name: autophagy related 4B cysteine peptidase<br />Also known as: APG4B; AUTL1; HsAPG4B<br />Autophagy is the process by which endogenous proteins and damaged organelles are destroyed within cells. Autophagy is considered essential for cellular homeostasis and cellular remodeling during cellular differentiation, metamorphosis, non-apoptotic cell death, and senescence. Reduced levels of autophagy have been described in some malignancies and a role for autophagy in the control of unregulated cell growth associated with cancer has been proposed. This gene encodes a member of the autophagy protein family. The encoded protein has also been designated as a member of the C-54 cysteine protease family. Alternative transcriptional splice variants encoding different isoforms have been characterized.