Analysis of MMP26 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2287-LGZ)

Introduction

Official Full Name: matrix metallopeptidase 26<br />Matrix metalloproteinase (MMP) family proteins are involved in the breakdown of the extracellular matrix during normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as disease processes such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature enzyme. The enzyme degrades type IV collagen, fibronectin, fibrinogen, and β-casein and activates matrix metalloproteinase-9 by cleavage. This protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The encoded protein may promote cell invasion in a variety of human cancers.