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Neuropeptide Y (NPY) is a hormone that widely exists in the central and peripheral and maintains homeostasis. In the center, NPY has anti-anxiety and anti-epileptic functions, and has the functions of inhibiting reproduction, inhibiting muscle excitation, and inhibiting sympathetic excitation, resulting in a decrease in blood pressure, heart rate, and metabolism of the human body. It can also promote appetite, and thus become the target of dieting drugs . However, peripheral NPY has a positive stimulatory effect, and it enhances the stress response together with glucocorticoids and catecholamines. NPY can induce vasoconstriction and vascular smooth muscle proliferation in the periphery, leading to elevated blood lipids, glucose tolerance, and the release of adipocytokines.