Gastric Cancer Animal Model (CAT#: STEM-AE-0092-WXH)

Research on the pathogenesis of gastric cancer and drug development.

• Induced gastric cancer model: N-methyl-N'-nitro-nitrosoguanidine (MNNG) and methylcholanthrene (MC) are commonly used.
• Transplanted gastric cancer model:
CDX model (cell-line-derived xenograft)-- inoculate human-derived gastric cancer cell lines into immunodeficient mice.
PDX model (patient-derived xenograft)--inoculate gastric cancer tissue blocks from patients To immunodeficient mice.
• Gastric cancer models in genetically engineered mice: including Tff1 knockout mice, INS-GAS transgenic mice, Gp130 mutant mice, H/K-ATPase:IL-1β transgenic mice and K-Ras transgenic mice.