IL-15 Detection (CAT#: STEM-MB-0283-WXH)

Introduction

IL-15 is a soluble cytokine. IL-15 can be expressed by monocytes, fibroblasts, macrophages, nerve cells, etc. It is a glycoprotein with a protein size of 14-15kDa. It acts as a chemokine for a variety of immune cells and participates in and regulates the body's inflammatory and immune responses. Its main biological activities are to stimulate T cell proliferation, regulate B cell proliferation and differentiation, regulate natural killer (NK) cells, and have obvious chemotactic effects on human peripheral blood mononuclear cells. In addition to the above effects, IL-15 can also play an important role in regulating lymphocyte function and homeostasis together with IL-2. Among them, the unique role of IL-2 is to clear autoreactive T cells and prevent itself from immune diseases occurring. On the contrary, IL-15 can maintain the immune response of memory T cells against pathogens for a long time, and it can also play an immune enhancing role in resisting worms and protozoal infections. As a pleiotropic cytokine, in addition to regulating the proliferation and differentiation of immune cells, IL-15 also has anti-apoptotic effects and is a powerful apoptosis inhibitor.