IL-17 Signaling Pathway Assay (CAT#: STEM-MB-0354-WXH)

Introduction

IL-17 is the main effector produced by Th17 cells and is essential for processes including host defense, tissue repair, pathogenesis of inflammatory diseases, and cancer progression. IL-17 can induce a variety of cells to release pro-inflammatory factors and neutrophil chemokines to adjust local tissue inflammation, and play an important role in the immune regulatory network. It has been proven to be related to asthma, tuberculosis, lung cancer and coronary arteries. Many diseases are related. The innate immune cells that produce IL-17 mainly include lymphoid tissue induced cells, natural killer cells, CD3+ stable natural killer T cells, γδT cells and myeloid cells. In addition, mast cells and neutrophils can also produce IL-17.