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Cartilage, or cartilage tissue, is made up of chondrocytes and intercellular matter. The matrix in the cartilage is gel and has greater toughness. Cartilage is a connective tissue that is primarily supportive. Cartilage does not contain blood vessels and lymphatic vessels, nutrients from the blood vessels in the perichondrium penetrate into the intercellular stroma, and then nourish bone cells.
Bone cells are the main cells in mature bone tissue, which is equivalent to the adult stage of human, and are transformed from osteoblasts. When the new bone matrix calcifies, the cells become embedded in it. At this point, the synthesis of cells stops, and the cytoplasm is reduced, becoming bone cells. Bone cells play a role in both bone resorption and bone formation and are the main cells that maintain the metabolism of mature bone.