RBP4 Signaling Pathway Assay (CAT#: STEM-MB-0377-WXH)

Introduction

Retinol binding protein4 (RBP4) is a newly discovered cytokine that belongs to the retinol binding protein (RBP) family and is mainly secreted by the liver and to a lesser extent by adipose tissue. In both animal and human studies, RBP4 has been found to play a key role in the development and progression of type 2 diabetes mellitus (T2DM), non-alcoholic fatty liver disease and atherosclerosis by participating in the regulation of glucose uptake and gluconeogenesis, and promoting insulin resistance.