Sox2 Signaling Pathway Luminex Assay (CAT#: STEM-MB-0329-WXH)

Introduction

The Sox gene family encodes a set of transcription factors that are evolutionarily conserved and structurally highly related to SRY (Y chromosome sex determining region), which regulates important life events such as early embryonic development, neural differentiation, sex orientation, and cell growth. At present, more than 20 sox family members have been discovered and named internationally. Sox-2 belongs to the Sox gene family B group B1 subgroup. It is located at 3q36.3-27. It is a single exon structure, which encodes and expresses 317 amino acid residues. The protein sox-2 is very important for the early development and maintenance of undifferentiated embryonic stem cells. sox is one of the key transcription factors originally used to obtain inducible pluripotent cells from fibroblasts, and sox-2 Gene overexpression or gene amplification is associated with the development of many cancers.