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Tumor necrosis factor (TNF) is a cytokine produced naturally by macrophages in response to bacterial infection or other immune sources. Mainly produced by activated monocytes/macrophages, it can kill and inhibit tumor cells, promote neutrophil phagocytosis, fight infection, cause fever, induce acute protein synthesis in hepatocytes, and promote myeloid leukemia cells to differentiate into macrophages It promotes cell proliferation and differentiation, is an important inflammatory factor, and participates in the pathological damage of certain autoimmune diseases. Tumor necrosis factor (TNF) has a wide range of biological activities, and plays an important role in endotoxin shock, moxibustion, immune regulation, cell proliferation, cytotoxic activity and antiviral activity.