Antibody Characterization (CAT#: STEM-MB-0141-WXH)

Introduction

Antibody characterization is important in research and biopharmaceutical development. All therapeutic proteins produced from current technologies have heterogeneities in the final product because various modifications occur during different stages of production. Due to these heterogeneities, thorough characterization is necessary for the reproducible and safe production of therapeutic proteins.

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Principle Applications Procedure Materials Notes Related Products

Applications

Necessary for the reproducible and safe production of therapeutic proteins.

Procedure

The basic mAb characterization workflows consist of the following types of analysis:

• Molecular weight determination of intact and reduced protein
• Peptide mapping
• Co- and post-translational modification mapping
• Acquired non-biological modifications
• Disulfide bond mapping

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