Chemerin Pathway Assay (CAT#: STEM-MB-0367-WXH)

Introduction

Chemerin is a newly discovered adipokine that is mainly secreted by adipose tissue in an autocrine or paracrine form. Chemerin affects glucolipid metabolism by binding to its receptor, recruiting inflammatory cells, regulating insulin sensitivity and adipocyte differentiation. Therefore, Chemerin may play an important role ian obesity, metabolic syndrome and osteoporosis. In addition, Chemerin is closely associated with cardiovascular diseases, tumors, non-alcoholic fatty liver, polycystic ovary syndrome and psoriasis, and can be secreted by adipocytes, act on its own receptor CMKLR1 via the autocrine pathway to promote adipocyte differentiation and glucose transport, and act on inflammatory response cells (e.g. macrophages) via the paracrine pathway, which may be a new therapeutic This may be a new target for the treatment of related diseases.