The effective transport of NPs through extracellular barriers, such as mucus and interstitium, may be critically important in order to achieve the desired therapeutic and/or diagnostic goals.
Particle tracking can be an invaluable tool to probe the quantitative transport properties of engineered nanomaterials as they move through these complex barriers. Information gathered from particle-tracking experiments can feedback into the design process to improve NP p hysicochemical properties and reach design aims.