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Osteoporosis is a clinically common disease, one of its symptoms is thinning of cortical bone thickness. The propagation speed of ultrasound is very sensitive to changes in the thickness of the measurement object, so it is possible to use ultrasound to measure the thickness of cortical bone and thereby diagnose osteoporosis. However, due to the complex propagation of ultrasound in cortical bone, signals of multiple guided wave modes are often superimposed on each other. How to extract and identify different guided wave modes from received signals and accurately calculate the thickness of cortical bone has become one of the research hotspots in this field.