Object Recognition Test (CAT#: STEM-AE-0018-WXH)

Introduction

The new object recognition test (object recognition test) is a learning and memory test method established by using the principle that animals have an innate tendency to explore new objects. This method has the characteristic of allowing mice to perform learning and memory tests in a free-moving state, and can more closely simulate human learning and memory behaviors. At the same time, the experiment also allows testing the formation of long-term or short-term memory mechanisms in animals and the evaluation of the impact of acute drugs on memory formation at specific stages through the flexible transformation of new objects (shape, size, etc.).

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Principle Applications Procedure Materials Notes Related Products

Applications

• Study on Learning and Memory
• Memory neurobiology research
• Research on the Mechanism of Brain Injury
• Research on protective measures for cognitive impairment

Procedure

1. Eliminate the strangeness with the testers and adapt to the test environment.
2. To start the training, put the two objects A and B on the left and right ends of the side wall, and put the rat back into the field with the two objects facing away. The rats were placed in for 10 minutes, and the contact between the rats and the two objects was recorded, including the number of times the nose or mouth touched the objects and the time spent exploring within the range of 2-3cm from the objects.
3. Immediately after the end, put the rat back into the original mouse box.
4. Start the test after the rat rests for a period of time. At this time, replace the B object in the field with the C object, and still turn the rat’s back to the two objects. The distance between the two objects is the same at the tip of the nose. Observe for 2-5 minutes, and the observation indicators are the same as step 2. Mainly observe the rats' exploration of the C object.

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