Recombinant Human TGF-β3 Protein, Seafrom (CAT#: STEM-CT-0034-ZJF)

The Recombinant Human TGF-β3 Protein manufactured by Seafrom is suitable for tissue regeneration, wound healing, and developmental processes.
Transforming Growth Factor-beta (TGF-β), including its isoforms TGF-β1, β2, and β3, signal through the same receptor, inducing similar biological responses. These multifunctional cytokines regulate cell proliferation, growth, differentiation, motility, and extracellular matrix synthesis and deposition. They play pivotal roles in various physiological processes, such as embryogenesis, tissue remodeling, and wound healing. Typically, they are secreted primarily as latent complexes and are stored on the cell surface and within the extracellular matrix. The release of bioactive TGF-β isoforms from latent complexes involves conformational changes induced by proteolysis, complex processing, and/or thrombospondin-1, among other protein-related conformational alterations. The exact physiological role of TGF-β3 is not yet fully understood, but its expression pattern suggests a regulatory role in certain developmental processes.
The lyophilized product can be stored at 2-8°C for 24 months. If reconstitution is required, it can be dissolved in injectable water, saline solution, culture medium, or PBS. After dissolution, it should be aliquoted, with a recommended storage period of 6 months at -20°C and 12 months at -80°C. When diluting, ensure a final concentration of no less than 100μg/mL, and avoid repeated freeze-thaw cycles.

Expression Host: HEK293 Cells
Synonyms: Transforming Growth Factor-β3
Protein Sequence: A301-S412, expressed with an Fc tag at the C-terminus
Predicted Molecular Weight: 42.1 kD
Purity: >90%, analyzed by SDS-PAGE
Endotoxin Level: <0.1 EU/μg
Biological Activity: Determined by inhibiting the proliferation of mouse HT-2 cells dependent on IL-4, ED50 ≤ 0.1 ng/mL
Purification Method: Chromatographic purification
Appearance: White loose body

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

Recombinant Human TGF-β1 Protein, Seafrom
Recombinant Human TGF-β2 Protein, Seafrom
Recombinant Human IFN-γ Protein, Seafrom
Recombinant Murine IFN-γ Protein, Seafrom