IL-18 Detection (CAT#: STEM-MB-0285-WXH)

Interleukin-18 (IL-18) also known as interferon-gamma inducing factor. It belongs to the IL-1 superfamily and is produced mainly by macrophages but also other cell types, stimulates various cell types and has pleiotropic functions. IL-18 is similar to IL-1β for being processed by caspase 1 to an 18 kD biologically active mature form. IL-18 is able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. And there is evidence for a role of IL-18 in various infectious, metabolic or inflammatory diseases such as influenza virus infection, atheroma, myocardial infarction, chronic obstructive pulmonary disease.

IL-18 is able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders.
IL-18 can promote the inflammatory response process.
IL-18 can stimulate the formation of blood vessels.
IL-18 can promote mitosis.
IL-18 can regulate the immune function of the host.

1. Process samples.
2. IL-18 detection (qPCR, Enzyme-linked immunosorbent assay (ELISA), Flow cytometry).
3. Analysis results.

Sample Types-Blood, serum, plasma, cerebrospinal fluid, cell culture supernatant, tissue homogenate, cell culture medium, urine, tumor, etc.