Adiponectin Signaling Pathway Assay (CAT#: STEM-MB-0366-WXH)

Lipocalin signaling promotes activation of PGC1 alpha and mitochondrial biogenesis. Lipocalin binding to Adipo R1 leads to calcium inward flow in skeletal muscle, which activates CaMKK β. Activated CaMKK β induces the expression and activation of PGC1 α through a cascade reaction that involves the activation of AMPK and increased production of SIRT1 deacetylase. AMPK phosphorylation and SIRT1 deacetylation of PGC1 α increase its transcriptional activity, leading to increased mitochondrial biogenesis.

Study the impact of each clinical virus on the adiponectin signaling pathway
Research on the regulatory mechanism of adiponectin signaling pathway in medicine

• Luminex Multiplex Assay
• Enzyme-linked immunosorbent assay (ELISA)
• Flow cytometry (FACS analysis) technology

Detectable targets: RTK, PI3K, TYK2, STAT1, STAT2, STAT3, PSGL1, IRS2, MSK1, TLR3, Tak1, TRIF, TNFR, ISGF3, MSK2, PI3K, TBK1, Vav, STAT5, IRAK4, JNK, MYD88, Rac1, TLR4, CD3, IRF5, MEK3, p38MAPK, SH2, TRAF6, CREB, IRF3, MAPK, NAP1, Rel, TLR9, p38, Fas, ISRE, mTOR, PKR, TRAF5, MHC-II, IRS1, MEK6, p50, SLP76, TRAM, TCR, icam1, Mda-5, NFκB, RIG-1, TRAF3, GAS, IRF9, MEKK1, RIP1