IFN-α Detection (CAT#: STEM-MB-0268-WXH)

Introduction

Interferon-alpha (IFN-α) is a group of structurally similar, functionally similar low molecular glycoproteins produced by antiviral response when the immune cells are infected with the virus. There are many IFN-α subtypes with molecular weights ranging from 15 to 21 kDa. IFN-α mainly have three functions: broad-spectrum antiviral effect, immunomodulatory effect, and anti-tumor effect, but the relative biological activity may be different. Since IFN-α has various anti-proliferative and anti-tumor activities, it is one of the most commonly used cytokine treatments for cancer patients with hairy cell leukemia, kidney cancer, Kaposi's sarcoma and other malignant tumors. Under physiological conditions, low levels of IFN-a can be detected. However, in infections and various pathological conditions, its production is significantly enhanced, making IFN-α a major disease marker.