IL-13 Detection (CAT#: STEM-MB-0282-WXH)

Introduction

Interleukin 13 (IL-13) is mainly secreted by activated CD4+ Th2 cells, and non-T cells such as mast cells, eosinophils and basophils can also produce IL-13. In the early allergic reaction, IL-13 mainly comes from natural killer T cells (NK cells). Its main biological function is to promote B cell proliferation and differentiation, induce B cell synthesis of IgE and expression of CD23, MHC class II molecules, downregulate cytotoxicity and inflammation of monocytes and macrophages, and play an important role in regulating immune and inflammatory responses. IL-13 has complex biological functions and participates in the occurrence and pathogenesis of various diseases. With the deepening of research, it has been found that IL-13 is closely related to dermatological diseases such as psoriasis, atopic dermatitis, lupus erythematosus, urticaria and allergic purpura. If it can be further studied its mechanism of action in related skin diseases, it will play an important role in promoting the development of dermatology.