IL-4 Detection (CAT#: STEM-MB-0273-WXH)

IL-4 is a dense, hydrophobic, spherical protein consisting of 129 amino acid residues. The biological effects of IL-4 are mediated by binding to its receptors, which are distributed in T cells, B cells, thymocytes, macrophages, bone marrow cells, macrophages and other cells. After binding to its receptor IR-4R, it can play a variety of biological functions, such as participating in the differentiation of primitive helper T cells, clearing parasites in the body, and triggering hypersensitivity. There are two types of IL-4 receptor (IL-4R): type I receptor complex IL-4Rα / IL-2Rγc and type II receptor complex IL-4Rα / IL-13Rα1. Type I receptors are mainly expressed on the surface of hematopoietic cells, and type II is often expressed on the surface of other cells such as non-hematopoietic cells and tumor cells.

IL-4 has an immune function and is an anti-inflammatory factor.
IL-4 plays a central role in regulating antigen-stimulated initial T cell differentiation.

1. Process samples.
2. IL-4 detection (qPCR, Enzyme-linked immunosorbent assay (ELISA), Flow cytometry).
3. Analysis results.

Sample Types-Blood, serum, plasma, cerebrospinal fluid, cell culture supernatant, tissue homogenate, cell culture medium, urine, tumor, etc.